any common client side scripts known to cause issues?

finally got tnext running and played for a few minutes. fucking awesome to have classic back and to see so many ppl on the servers.

my install is out of the box atm but when I get home from work im gonna install the scripts I usually play with. mostly just gui shit, pilot mode, some skins, demo shit, and the like....

any there scripts that have been causing people trouble?'